TXA indications include which of the following?

• A. Penetrating torso trauma
• B. Non-bleeding sprain
• C. Chronic cough
• D. Allergic reaction to pollen

Answer: (A)

The main concept is recognizing when tranexamic acid should be used to reduce hemorrhage in trauma. Tranexamic acid works by inhibiting plasmin formation, which slows the breakdown of clots and helps stabilize bleeding. In tactical care, it’s indicated for casualties with significant bleeding or a high risk of life‑threatening hemorrhage, with the best outcomes when given early (ideally within the first hour and no later than about three hours after injury). Penetrating torso trauma fits this scenario because injuries to the torso have a high risk of rapid, severe bleeding, so TXA can reduce mortality when administered promptly. The other scenarios—non‑bleeding sprain, chronic cough, and allergic reaction to pollen—do not involve active major bleeding or a hemorrhagic threat, so TXA isn’t indicated there.